Overview

If you are interested in learning more about PSFcheck slides, please follow this link

For publications, please see my Google Scholar page

I am a senior lecturer in fluorescence microscopy and joined the Biomedical Physics group in January 2016. My research investigates the application of advanced photonics techniques to medical imaging. Specifically I am interested in the development of new microscopy tools that can improve the specificity and spatiotemporal resolution of biomedical image data. Current projects include the rapid acquisition of three-dimensional data sets of excitable tissues and the development of coherent optical methods for dye-free optical imaging.  I am also interested in the development of quantitative methods in biomedical imaging, including the development of new calibration standards to place specific bounds on the accuracy of image data.

Education and Employment

• 2020 -              Senior Lecturer, University of Exeter

• 2016 - 2020     Lecturer, University of Exeter

• 2014 - 2015     Research Fellow, University of Oxford

• 2013 - 2013     Senior Engineer, Canon Information System Research Australia. 

• 2010 - 2012     Research Associate, University of Oxford

• 2007 - 2010     Senior Engineer, Light Blue Optics (spin-out)

• 2003 - 2008     PhD in Optical Engineering, University of Cambridge

• 1998 - 2002     MSci Natural Sciences, University of Cambridge

Research Funding

• Start | End | Scheme | Awarding body | PI/Co-I | FEC | REF Split | Grant Number 
• Aug-23 | Apr-24 | MRC IAA | MRC IAA| PI | £33,530 | £33,530 | N/A
• May-23 | Jul-23 | Collaboration Fund | Open Innovation Platform | PI | £14,928 | £14,928 | N/A
• Jul-22 | Jul-23 | ALERT 21 | BBSRC | Co-I | £974,653 | £38,986 | BB/W020335/1
• Feb-21 | Feb-22 | Short Industry Fellowship | Royal Society | PI | £24,764 | £24,764 | SIF\R2\202044
• Sep-20 | Feb-21 | CoA Fund | EPSRC | PI | £62,291 | £62,291 | EP/V520536/1
• Nov-19 | May-21 | Core Capital 2019 | EPSRC | Co-I | £269,363.00 | £76,832.40 | EP/T023635/1
• Jul-19 | Feb-20 | Impact Acceleration | EPSRC | PI | £54,243.00 | £32,735.00 | N/A
• Nov-18 | Oct-19 | Commercialisation | IMPACT LAB | PI | £15,000.00 | £15,000.00 | N/A
• Jun-18 | Sep-20 | First Grant | EPSRC | PI | £125,000.00 | £100,928.00 | EP/R021252/1
• Jun-18 | Sep-20 | Capital Equipment Fund | CEMPS | PI | £48,000.00 | £48,000.00 | N/A
• May-18 | Jul-18 | Proof of Concept | Open innovation | PI | £18,639.00 | £6,329.00 | N/A
• Nov-16 | May-17 | ICURe | SETSquared | PI | £50,000.00 | £32,000.00 | N/A
• Nov-16 | Jul-17 | Open Innovation | HEFCE | PI | £14,820.00 | £14,820.00 | N/A
• Feb-16 | Apr-16 | Equip grant | CEMPS | PI | £15,000.00 | £15,000.00 | N/A

Key publications

• Burton RAB, Klimas A, Ambrosi CM, Tomek J, Corbett A, Entcheva E, Bub G. (2015) “Optical control of excitation waves in cardiac tissue”, Nature Photonics, volume 9, no. 12, pages 813-816, DOI:10.1038/nphoton.2015.196.

• Corbett AD, Burton RAB, Bub G, Salter PS, Tuohy S, Booth MJ, Wilson T. (2014) "Quantifying distortions in two-photon remote focussing microscope images using a volumetric calibration specimen", Frontiers in Physiology, volume 5, DOI:10.3389/fphys.2014.00384.

• Botcherby EJ, Corbett A, Burton RAB, Smith CW, Bollensdorff C, Booth MJ, Kohl P, Wilson T, Bub G. (2013) "Fast Measurement of Sarcomere Length and Cell Orientation in Langendorff-Perfused Hearts Using Remote Focusing Microscopy", Circulation Research, volume 113, no. 7, pages 863-870, DOI:10.1161/CIRCRESAHA.113.301704.

• Reeve JE, Corbett AD, Boczarow I, Kaluza W, Barford W, Bayley H, Wilson T, Anderson HL. (2013) "Porphyrins for Probing Electrical Potential Across Lipid Bilayer Membranes by Second Harmonic Generation", Angewandte Chemie International Edition, volume 52, no. 34, pages 9044-9048, DOI:10.1002/anie.201304515.

• Reeve JE, Corbett AD, Boczarow I, Wilson T, Bayley H, Anderson HL. (2012) "Probing the Orientational Distribution of Dyes in Membranes through Multiphoton Microscopy", Biophysical Journal, volume 103, no. 5, pages 907-917, DOI:10.1016/j.bpj.2012.08.003.

Back to top

Publications

_{Copyright Notice: Any articles made available for download are for personal use only. Any other use requires prior permission of the author and the copyright holder.}

| 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2015 | 2014 | 2013 | 2012 | 2011 | 2009 | 2008 | 2007 | 2005 | Patents |

2023

• Metz J, Gintoli M, Corbett AD. (2023) Fully automated point spread function analysis using PyCalibrate, Biology Open, volume 12, no. 11, DOI:10.1242/bio.059758. [PDF]
• Corbett A. (2023) Fully automated point spread function analysis using PyCalibrate (dataset).
• Mohanan S, Corbett AD. (2023) Understanding the limits of remote focusing, Optics Express, volume 31, no. 10, pages 16281-16294, DOI:10.1364/oe.485635.
• Mohanan S, Corbett A. (2023) Understanding the limits of remote focusing (dataset).

2022

• Mohanan S, Corbett AD. (2022) Understanding the limits of remote focusing. [PDF]
• Metz J, Gintoli M, Corbett A. (2022) Fully Automated Point Spread Function Analysis Using Pycalibrate, DOI:10.1101/2022.10.11.511725.
• Nelson G. (2022) Monitoring the point spread function for quality control of confocal microscopes v1, DOI:10.17504/protocols.io.bp2l61ww1vqe/v1. [PDF]
• Mohanan S. (2022) Remote Focusing in Optical Microscopy.
• Hammer M, Huisman M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P. (2022) Author Correction: Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model, Nat Methods, volume 19, no. 2, DOI:10.1038/s41592-021-01386-y. [PDF]

2021

• Nelson G, Boehm U, Bagley S, Bajcsy P, Bischof J, Brown CM, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O. (2021) QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy, DOI:10.48550/arxiv.2101.09153.
• Hammer M, Huisman M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P. (2021) Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model, Nat Methods, volume 18, no. 12, pages 1427-1440, DOI:10.1038/s41592-021-01327-9. [PDF]
• Hammer M, Huisman M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P. (2021) Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model, DOI:10.1101/2021.04.25.441198.
• Nelson G, Boehm U, Bagley S, Bajcsy P, Bischof J, Brown CM, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O. (2021) QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy, J. Microsc. 2021;1-18. [PDF]
• Ashraf M, Mohanan S, Sim BR, Tam A, Rahemipour K, Brousseau D, Thibault S, Corbett AD, Bub G. (2021) Random access parallel microscopy, eLife, volume 10, DOI:10.7554/elife.56426. [PDF]

2020

• Gintoli M, Mohanan S, Salter P, Williams E, Beard JD, Jekely G, Corbett AD. (2020) Spinning Disk -- Remote Focusing Microscopy, DOI:10.48550/arxiv.2002.06576.
• Mohanan S, Corbett AD. (2020) Sensitivity of Remote Focusing Microscopes to Magnification Mismatch, DOI:10.48550/arxiv.2009.12136.
• Mohanan S, Corbett AD. (2020) Sensitivity of Remote Focusing Microscopes to Magnification Mismatch. [PDF]
• Corbett A, Mohanan S. (2020) Sensitivity of Remote Focusing Microscopes to Magnification Mismatch (data set). [PDF]
• Corbett A, Gintoli M, Mohanan S, Williams E, Jekely G, Salter PS. (2020) Spinning Disk - Remote Focusing Microscopy (data set). [PDF]
• Gintoli M, Mohanan S, Salter P, Williams E, Beard JD, Jekely G, Corbett AD. (2020) Spinning disk-remote focusing microscopy, Biomedical Optics Express, volume 11, no. 6, pages 2874-2874, DOI:10.1364/boe.389904. [PDF]

2019

• Ashraf M, Mohanan S, Sim B, Tam A, Brousseau D, Thibault S, Corbett A, Bub G. (2019) Solid State High Throughput Screening Microscopy, DOI:10.1101/602011.
• Huisman M, Hammer M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P. (2019) A perspective on Microscopy Metadata: data provenance and quality control. [PDF]
• Lawton PF, Buckley C, Saunter CD, Wilson C, Corbett AD, Salter PS, McCarron JG, Girkin JM. (2019) Multi-plane remote refocusing epifluorescence microscopy to image dynamic Ca<i/>²⁺events, Biomedical Optics Express, volume 10, no. 11, pages 5611-5611, DOI:10.1364/boe.10.005611. [PDF]

2018

• Corbett AD, Shaw M, Yacoot A, Jefferson A, Schermelleh L, Wilson T, Booth M, Salter PS. (2018) Microscope calibration using laser written fluorescence, DOI:10.48550/arxiv.1806.05457.
• Corbett AD. (2018) Microscope calibration using laser written fluorescence.
• Corbett AD, Shaw M, Yacoot A, Jefferson A, Schermelleh L, Wilson T, Booth M, Salter PS. (2018) Microscope calibration using laser written fluorescence, Optics Express, volume 26, no. 17, pages 21887-21899, DOI:10.1364/OE.26.021887.

2017

• Burton RAB, Rog-Zielinska EA, Corbett AD, Peyronnet R, Bodi I, Fink M, Sheldon J, Hoenger A, Calaghan SC, Bub G. (2017) Caveolae in Rabbit Ventricular Myocytes: Distribution and Dynamic Diminution after Cell Isolation, Biophysical Journal, volume 113, no. 5, pages 1047-1059, DOI:10.1016/j.bpj.2017.07.026.
• Li B, Corbett AD, Chong E, Mann EO, Wilson T, Booth MJ, Bub G. (2017) Toward multi-focal spot remote focusing two-photon microscopy for high speed imaging, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIV, Proceedings of SPIE, volume 10070, DOI:10.1117/12.2251214.

2015

• Corbett AD, Burton RAB, Bub G, Wilson T. (2015) Uniquely identifying cell orientation and sarcomere length in the intact rodent heart with oblique plane remote focussing microscopy, Advanced Microscopy Techniques IV; and Neurophotonics II, DOI:10.1364/ecbo.2015.95360a.
• Corbett AD. (2015) Uniquely identifying cell orientation and sarcomere length in the intact rodent heart with oblique plane remote focussing microscopy, European Conferences on Biomedical Optics, DOI:10.1117/12.2183843.
• Corbett AD. (2015) Quantitative imaging of intact cardiac tissue using remote focusing microscopy, San Francisco, California, United States, DOI:10.1117/12.2076133.
• Corbett AD. (2015) Imaging cardiomyocytes in intact tissue with a remote focusing microscope, San Francisco, California, United States, DOI:10.1117/12.2087342.
• Corbett AD, Bub G. (2015) Bringing the living brain into focus, Nature Photonics, volume 9, no. 2, pages 80-82, DOI:10.1038/nphoton.2015.3. [PDF]
• Burton RAB, Klimas A, Ambrosi CM, Tomek J, Corbett A, Entcheva E, Bub G. (2015) Optical control of excitation waves in cardiac tissue, Nature Photonics, volume 9, no. 12, pages 813-816, DOI:10.1038/nphoton.2015.196. [PDF]

2014

• Corbett AD, Burton RAB, Bub G, Salter PS, Tuohy S, Booth MJ, Wilson T. (2014) Quantifying distortions in two-photon remote focussing microscope images using a volumetric calibration specimen, Frontiers in Physiology, volume 5, DOI:10.3389/fphys.2014.00384. [PDF]

2013

• Reeve JE, Corbett AD, Boczarow I, Kaluza W, Barford W, Bayley H, Wilson T, Anderson HL. (2013) Porphyrins for Probing Electrical Potential Across Lipid Bilayer Membranes by Second Harmonic Generation, Angewandte Chemie, volume 125, no. 34, pages 9214-9218, DOI:10.1002/ange.201304515.
• Reeve JE, Corbett AD, Boczarow I, Kaluza W, Barford W, Bayley H, Wilson T, Anderson HL. (2013) Porphyrins for Probing Electrical Potential Across Lipid Bilayer Membranes by Second Harmonic Generation, Angewandte Chemie International Edition, volume 52, no. 34, pages 9044-9048, DOI:10.1002/anie.201304515. [PDF]
• Botcherby EJ, Corbett A, Burton RAB, Smith CW, Bollensdorff C, Booth MJ, Kohl P, Wilson T, Bub G. (2013) Fast Measurement of Sarcomere Length and Cell Orientation in Langendorff-Perfused Hearts Using Remote Focusing Microscopy, Circulation Research, volume 113, no. 7, pages 863-870, DOI:10.1161/circresaha.113.301704. [PDF]

2012

• Reeve JE, Corbett AD, Boczarow I, Wilson T, Bayley H, Anderson HL. (2012) Probing the Orientational Distribution of Dyes in Membranes through Multiphoton Microscopy, Biophysical Journal, volume 103, no. 5, pages 907-917, DOI:10.1016/j.bpj.2012.08.003. [PDF]

2011

• Corbett A, Bub G, Wilson T. (2011) In-Situ measurement of sarcomere length in cardiac myocytes using a two-photon microscope with near-isotropic scan rate, Optics InfoBase Conference Papers, DOI:10.1364/ntm.2011.nmd1.
• Corbett A, Bub G, Wilson T. (2011) In-Situ measurement of sarcomere length in cardiac myocytes using a two-photon microscope with near-isotropic scan rate, Optics InfoBase Conference Papers.

2009

• Buckley E, Corbett A, Surman P, Sexton I, Hopf K, Neumann F. (2009) Multi-viewer autostereoscopic display with dynamically addressable holographic backlight, Journal of the Society for Information Display, volume 17, no. 4, pages 345-356, DOI:10.1889/JSID17.4.345.

2008

• Surman P, Sexton I, Hopf K, Lee WK, Neumann F, Buckley E, Jones G, Corbett A, Bates R, Talukdar S. (2008) Laser-based multi-user 3-D display, Journal of the Society for Information Display, volume 16, no. 7, pages 743-753, DOI:10.1889/1.2953481.
• Buckley E, Corbett A, Surman P, Sexton I. (2008) Distinguished paper: Multi-viewer autostereoscopic display with dynamically-addressable holographic backlight, Digest of Technical Papers - SID International Symposium, volume 39, no. 1, pages 340-344, DOI:10.1889/1.3069664.

2007

• Corbett AD, Wilkinson TD, Zhong JJ, Diaz-Santana L. (2007) Designing a holographic modal wavefront sensor for the detection of static ocular aberrations, Journal of the Optical Society of America A, volume 24, no. 5, pages 1266-1266, DOI:10.1364/josaa.24.001266. [PDF]

2005

• Zhong JJ, Leyva DG, Corbett AD, Diaz-Santana L, Wilkinson TD. (2005) Mirror-mode sensing with a holographic modal wavefront sensor, Proceedings of SPIE - The International Society for Optical Engineering, volume 6018, DOI:10.1117/12.669389.
• Corbett AD, Gil Leyva D, Diaz-Santana L, Wilkinson TD, Zhong JJ. (2005) Ctaractersing a holographic modal phase mask for the detection of ocular aberrations, Proceedings of SPIE - The International Society for Optical Engineering, volume 6018, DOI:10.1117/12.669247.

Patents

• Corbett AD, Routley PR, Cable AJ, McCaughan GJ. Holographic image display systems, Patent Number: US20110002019 A1, 2011.
• Corbett AD, Lacoste L, Stindt D. Laser Based Image Display System, Patent Number: US20120002256 A1, 2012.
• Corbett AD, Bone DJ. Rotational phase unwrapping, Patent Number: US 20150139385 A1, US, 2015.

Back to top