At the moment adminemail.pl allows an email address to be configured for the repository as a whole rather than individual repository admins. This email address is used for many different purposes:

1. As the sender (from) address used for email sent out responding to user requests.
2. On default static web pages as a contact email address.
3. The Apache server configuration admin email. If there is a webserver error (e.g. an internal server error) it is likely this email address will be displayed in the error message page.
4. The recipient (to) address of request removal emails, if the individual eprint does not have a contact email address set.
5. As part of the message body for reset password emails (as well as being the sender address), so the user can contact someone if there is a problem resetting their password.
6. In the message body of request a copy emails, as a way to make contact if their request a copy is not responded to,
7. In the message body of request a copy rejection emails.
8. In the mail signature in the message body of most emails sent out by a repository.

One particular issue may be that you don't want the sender of emails from you repository to be a real email address. This is not just because you don't want it to receive spam from bots that send replies to automate request copy emails they receive but that is means these request copy emails may not reach recipients on the same domain as the sender due to DMARC restrictions.

For now the best solution seem to be to have a sender email address that will be the same as the admin email address unless specifically set.