HIV & AIDS

Perinatal transmission of HIV can lead to cognitive deficits

Perinatal transmission of HIV to newborns is associated with serious cognitive deficits as children grow older, according to a detailed analysis of 35 studies conducted by Georgetown University Medical Center neuroscientists. ...

Immunology

How B cells recognize new variants of SARS-CoV-2

B cells are part of the immune system's memory. Their memories of previous infections or vaccinations provide the template for antibodies that have a protective effect the next time they come into contact with a pathogen.

Diseases, Conditions, Syndromes

Computer prompts could reduce empiric antibiotic use for UTI

For non-critically ill patients with urinary tract infection (UTI), computerized provider order entry (CPOE) prompts providing patient- and pathogen-specific multidrug-resistant organism (MDRO) risk estimates can reduce empiric ...

Diseases, Conditions, Syndromes

Effective malaria prevention in pregnant women despite drug resistance

Sulfadoxine-pyrimethamine (SP) retains parasitological activity and remains effective for preventing P. falciparum infection in pregnant women and low birth weight in babies, even in areas with a high prevalence of mutations ...

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Infection

An infection is the detrimental colonization of a host organism by a foreign species. In an infection, the infecting organism seeks to utilize the host's resources to multiply, usually at the expense of the host. The infecting organism, or pathogen, interferes with the normal functioning of the host and can lead to chronic wounds, gangrene, loss of an infected limb, and even death. The host's response to infection is inflammation. Colloquially, a pathogen is usually considered a microscopic organism though the definition is broader, including parasites, fungi, viruses, prions, and viroids. A symbiosis between parasite and host, whereby the relationship is beneficial for the former but detrimental to the latter, is characterised as parasitism. The branch of medicine that focuses on infections and pathogens is infectious disease. "When infection attacks the body, anti-infective drugs can help turn the tide of battle. Four types of anti-infective drugs exist: antibacterial, antiviral, antitubercular, and antifungal. A secondary infection is an infection that occurs during or following treatment of another already existing primary infection.

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