Institute of Psychiatry, Psychology & Neuroscience

Dr Nicolás Marichal receives an Emerging Leadership Fellowship Award from Epilepsy Research Institute UK. The grant supports the project "Reprogramming of reactive glia into fast-spiking interneurons in a mouse model of Mesial Temporal Lobe Epilepsy" In this project, Dr Marichal and co-investigator Professor Benedikt Berninger will investigate the possibility of regenerating inhibitory neurons from other, non-neuronal cells to reduce seizure activity in temporal lobe epilepsy, one of the most common forms of chronic epilepsy. Temporal lobe epilepsy often remains untreatable with current antiseizure medications, creating an urgent need for novel treatment strategies.

A new landmark study, funded by us and the Medical Research Council, reveals important insights into how digital technology is being used by young people with lived experience of mental health conditions. Led by Dr Rina Dutta at King’s Institute of Psychiatry, Psychology & Neuroscience, the study recruited over 300 young people accessing mental health services in South-East London, to uncover comprehensive details about social media and smartphone use, and its links with self-harm. 🤳 The study found that 80% of all participants had self-harmed at least once, and that high levels of depression, anxiety, and disturbed sleep were all prevalent. 🌙 More than half reported using social media or their smartphones after midnight on a weekday. 🤝 With support from the Foundation and in partnership with YoungMinds, Dr Dutta’s study provides a basis for researchers to conduct thorough investigations in this field, helping to bring about better support for young people who are struggling with their mental health. Read the full story: https://lnkd.in/euuS8ssC #MentalHealth #AdolescentMentalHealth #SmartPhoneUse #SelfHarmSupport #MentalHealthAwareness #YoungMindsUK #MedicalResearch

What is early intervention for #eatingdisorders and how has it revolutionised care for patients and families? Join us to learn and celebrate 10 years of FREED project that has sparked worldwide movement. 

New research from the NIHR Maudsley Biomedical Research Centre (BRC), in partnership with YoungMinds, has found high levels of problematic mobile phone use, disturbed sleep, and self-harm among young people with mental health conditions. The study’s innovative design, led by Dr Rina Dutta and Dr Amanda Bye PhD AFHEA, has laid the groundwork for more thorough research into the impact of digital technology on youth mental health in the future. Click the link to learn more 👇 #IoPPNNews #MentalHealth #MentalHealthAwareness #Research #YoungPeople #PopulationHealth https://lnkd.in/eqNqS_Xa

New research from Social, Genetic & Developmental Psychiatry Centre has found that DNA sequences which originate from ancient viral infections contribute to susceptibility for psychiatric disorders like schizophrenia, bipolar disorder and depression. The research was published in Nature Communications and funded by NIHR Maudsley Biomedical Research Centre (BRC) and the National Institutes of Health. It is the first to show that a set of specific HERVs (are products of ancient viral infections) expressed in the human brain contribute to psychiatric disorder susceptibility. Read the full story 👉 https://lnkd.in/ehicwtHV #KingsIoPPN #IoPPNNews #Genetics #DNA #Psychiatry #MentalHealth #PsychiatricGenetics King's College London | King's Health Partners | Northwell Health | Timothy Powell | Rodrigo R R Duarte | NIHR (National Institute for Health and Care Research)

DATAMIND is being showcased at the Health Data Research UK (HDR UK) Alliance Transparency Showcase today!   With funding from the Medical Research Council, researchers Hannah Lewis, Maria Jose Rodriguez Pinzon and Elena Triantafillopoulou worked closely with people with lived experience of mental health difficulties to foster transparency, accessibility and engagement in longitudinal health research. Learn more 👇   #UKHealthDataResearchAlliance #TransparentDataAccess Louise Arseneault Malaika O. King's Health Partners King's College London https://lnkd.in/eyyb3v6G

About eight per cent of our genome is comprised of sequences called Human Endogenous Retroviruses (HERVs), which are products of ancient viral infections that occurred hundreds of thousands of years ago. Until recently, it was assumed that these ‘fossil viruses’ were simply junk DNA, with no important function in the body. 🔬 Due to advances in genomics research, scientists have now discovered where in our DNA these fossil viruses are located, enabling us to better understand when they are expressed and what functions they may have. 🧠 A new study part-funded by our NIHR (National Institute for Health and Care Research) Maudsley BRC and led by Dr Timothy Powell and Dr Rodrigo R R Duarte has shown a link between this ancient viral DNA and psychiatric disorders. 📑 Published in Nature Portfolio Communications, this improved understanding of these ancient viruses, and the known genes implicated in psychiatric disorders, has the potential to revolutionise mental health research and lead to novel ways to treat or diagnose these conditions. Read the full story here https://lnkd.in/eXSDeeNp Institute of Psychiatry, Psychology & Neuroscience | King's College London | Social, Genetic & Developmental Psychiatry Centre | King's Health Partners | Deepak P. Srivastava | Oliver Pain, PhD | Claire Troakes | Sashika Selvackadunco | Matthew Bendall | Paul O'Reilly | Miguel de Mulder Rougvie | Weill Cornell Medicine

Congratulations to King's Professors Ammar Al-Chalabi, Maddy Parsons and Jane Sandall, newly elected as Fellows of The Academy of Medical Sciences. The researchers have been elected in recognition of their work advancing biomedical and health sciences in the fields of neuroscience, cell biology and women's health. King's Faculty of Life Sciences & Medicine Institute of Psychiatry, Psychology & Neuroscience Read more ⬇️ https://lnkd.in/eEX7ym2X

Delighted to announce our first keynote speaker for the EPSRC DRIVE-Health CDT's summer symposium next month. Dr Dina Demner-Fushman joins us from the National Library of Medicine (NLM) to talk about "Getting AI generated results into decision support workflows: research, clinical and policy perspectives." Dina will share insights drawn from her experience utilising a Clinical Decision Support (CDS) tab within the National Institutes of Health's EHR system, and present recent research on the application of LLMs for predicting patient outcomes and generating progress notes. Find more event details 👉https://lnkd.in/eN5y-Nia

IoPPN researchers have received over £4.8m new funding from Wellcome Trust to investigate the genetic and cognitive mechanisms which determine who benefits from psychological treatments for anxiety, and why. 🧬 Read the full story 👉 https://lnkd.in/efWM9xeH #MentalHealthAwarenessWeek #KingsIoPPN #IoPPNNews #ResearchFunding #HealthResearch #Anxiety #Genetics #Cognition #MentalHealth | King's College London | King's Health Partners | NIHR Maudsley Biomedical Research Centre (BRC) | NIHR BioResource | GLAD Study (Genetic Links to Anxiety and Depression Study) | TEDS Environment Study | Social, Genetic & Developmental Psychiatry Centre | Thalia Eley | Gerome Breen | Colette Hirsch