The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome
Abstract
:1. Introduction
2. Materials and Methods
3. Results
Sensitivity Analysis
4. Discussion
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
Abbreviations
OPSOC | Older Persons Surgical Outcomes Collaboration |
CAM | Confusion Assessment Method |
MoCA | Montreal Cognitive Assessment |
References
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CAM 411 (100%) | MoCA 411 (100%) |
---|---|
Delirious 36 (8.8) | Fail = score ≤ 25 253 (70.3) |
Not delirious 367 (89.3) | Pass = score ≥ 26 103 (16.3) |
Missing 8 (1.9) | Incomplete 55 (13.4) |
Included Patient Characteristics | Non-Delirious Group (CAM Negative) N = 367 (%) | Delirious Group (CAM Positive) N = 36 (%) | Total N = 403 | Test Statistic | ||
---|---|---|---|---|---|---|
Age | Mean (S.D) | 76.9 (8.0) | 81.6 (7.9) | 77.3 (8.1) | p = 0.001 | |
Sex | Male | 175 (47.7) | 19 (52.8) | 194 | 403 | p = 0.683 |
Female | 192 (52.3) | 17 (47.2) | 209 | |||
Polypharmacy (≥5 medications) | Yes | 246 (67.0) | 27 (75.0) | 273 | 403 | p = 0.329 |
No | 121 (33.0) | 9 (25.0) | 130 | |||
Anaemia (Hb < 129 g/L) | Yes | 161 (43.9) | 18 (50.0) | 179 | 403 | p = 0.596 |
No | 206 (56.1) | 18 (50.0) | 224 | |||
Hypoalbuminemia (Albumin < 35 g/L) | Yes | 153 (41.7) | 13 (36.1) | 166 | 403 | p = 0.637 |
No | 214 (58.3) | 23 (63.9) | 237 | |||
Operation | Yes | 70 (19.1) | 7 (19.4) | 77 | 403 | p = 0.937 |
No | 290 (79.0) | 28 (77.8) | 318 | |||
Missing | 7 (1.9) | 1 (2.8) | 8 |
Cohort Outcomes | Delirious Group (CAM Positive) N = 36 (%) | Non-Delirious Group (CAM Negative) N = 367 (%) | Total N = 403 | Unadjusted OR (95% CI) | Adjusted OR * (95% CI) | ||
---|---|---|---|---|---|---|---|
Death at 30 days | Dead | 2 (5.6) | 18 (4.9) | 20 | 403 | 1.14 (0.25–5.13) p = 0.70 | 0.80 (0.23–2.83) p = 0.73 |
Alive | 34 (94.4) | 349 (95.1) | 383 | ||||
Death at 90 days | Dead | 4 (11.1) | 31 (8.5) | 35 | 402 | 1.35 (0.45–4.07) p = 0.82 | 0.41 (0.07–2.59) p = 0.34 |
Alive | 32 (88.9) | 335 (91.5) | 367 | ||||
Readmission 30 days after discharge | Yes | 7 (19.4) | 75 (20.4) | 82 | 403 | 0.94 (0.40–2.23) p = 0.89 | 0.59 (0.17–2.11) p = 0.42 |
No | 29 (80.6) | 292 (79.6) | 321 |
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Hewitt, J.; Owen, S.; Carter, B.R.; Stechman, M.J.; Tay, H.S.; Greig, M.; McCormack, C.; Pearce, L.; McCarthy, K.; Myint, P.K.; et al. The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome. Geriatrics 2019, 4, 57. https://doi.org/10.3390/geriatrics4040057
Hewitt J, Owen S, Carter BR, Stechman MJ, Tay HS, Greig M, McCormack C, Pearce L, McCarthy K, Myint PK, et al. The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome. Geriatrics. 2019; 4(4):57. https://doi.org/10.3390/geriatrics4040057
Chicago/Turabian StyleHewitt, Jonathan, Stephanie Owen, Ben R. Carter, Michael J. Stechman, Hui Sian Tay, Matthew Greig, Caroline McCormack, Lyndsay Pearce, Kathryn McCarthy, Phyo K. Myint, and et al. 2019. "The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome" Geriatrics 4, no. 4: 57. https://doi.org/10.3390/geriatrics4040057