Dr Ellie Edlmann
Profiles

Dr Ellie Edlmann

Clinical Lectureship in Neurosurgery

Peninsula Medical School (Faculty of Health)

Dr Ellie Edlmann can be contacted through arrangement with our Press Office, to speak to the media on these areas of expertise.
  • Neuroscience
  • Ageing
  • Clinical trials
  • Delphi method
  • Randomised controlled trials
Biography

Biography

I am a senior registrar and academic working in neurosurgery. I spend 50% of my time in clinical neurosurgery at University Hospitals Plymouth NHS Trust, with a special interest in brain tumours and traumatic brain injuries. The other 50% of my time is focused on research in neurosurgical patients, around clinical trials, older people and traumatic injuries. 

I have previously led on the Dex-CSDH clinical trial which was a national, multi-site randomised controlled trial of dexamethasone for patients with Chronic Subdural Haematoma. Following this I was a co-applicant on the DENS trial, for older people with cervical fractures randomising to early or late removal of a collar and am the PI of this study in Plymouth. 

I also helped design and am a co-applicant on the RESTART-tICH trial which is due to commence next year as a multi-site UK trial randomising to early or late recommencement of blood thinners (DOACs) after a traumatic intracranial haemorrhage. 

I continue to conduct research in the field of Chronic Subdural haematoma including development of a core outcome set, qualitative research on patient pathways and recovery and am part of a national working group developing guidelines in this area (ICENI). 

Qualifications

2023: Awarded FRCS Neurosurgery, Royal College of Surgeons of England

2019 -24: Clinical lecturer in Neurosurgery, University of Plymouth

2017: Awarded AFHEA (Associate Fellow of the Higher Education Academy)      

2015-18: Clinical Neurosciences PhD & neurosurgery research fellow, Wolfson College, University of Cambridge 

2011: Started national training number in Neurosurgery, South West Peninsula 

2010: Awarded MRCS, Royal college of Surgeons of England

2008 - 10: Foundation training, South Thames, London, UK

2008: Bachelor of Medicine, Bachelor of Surgery (BM BS) with honours, Brighton and Sussex Medical School, Brighton, UK

Professional membership

  • Royal College of Surgeons of England (RCS)
  • Society of British Neurological Surgeons (SBNS)
  • European Association of Neurosurgical Societies (EANS)
  • Associate Fellow of the Higher Education Academy (AFHEA)

Roles on external bodies

I am currently the national associate sub-specialty lead for neurosurgery at the Royal College of Surgeons which involves helping to support and promote academic activity and clinical trials throughout neurosurgery in the UK. I am also the local PI for the DENS trial in Plymouth and Co-PI for the MAST trial.

I am a founding member and co-chair of the International Collaborative Research Initiative on Chronic Subdural Haematoma (iCoRIC) study group; www.icoric.org

Previously I have been the trainee representative on the specialty advisory committee (SAC) for Neurosurgery (2018-20) and chair of the British Neurosurgical Trainees Research Collaborative (BNTRC) in 2017.

Key publications

Edlmann E, Whitfield PC, Kolias A & Hutchinson PJ (2021) 'Pathogenesis of Chronic Subdural Hematoma: A Cohort Evidencing De Novo and Transformational Origins' Journal of Neurotrauma 38, (18) 2580-2589 , DOI Open access
Hutchinson PJ, Edlmann E, Bulters D, Zolnourian A, Holton P, Suttner N, Agyemang K, Thomson S, Anderson IA & Al-Tamimi YZ (2020) 'Trial of Dexamethasone for Chronic Subdural Hematoma' New England Journal of Medicine 383, (27) 2616-2627 , DOI Open access
View all publications
Teaching

Teaching

Teaching interests

I am interested in teaching medical students, junior doctors and allied health professionals on any areas relating to neurosurgery, neuroanatomy or research in this field. I am also a mentor for academic trainees and students interested in a career in neurosurgery and support projects and publications. 

Research

Research

Research interests

My main research interests have been in the field of head injury and neurosurgery in older patients. During my PhD I worked on the national Dex-CSDH trial which recruited 750 patients to a randomised study on dexamethasone versus placebo to treat chronic subdural haematoma. I have continued this interest in looking at the role of anti-thrombotic medications in head injury. 

I have also helped establish an international collaborative research initiative on chronic subdural haematoma (iCORIC) which meets annually and shares research ideas, methodology and is planning future studies. I am also a member of the trial steering committee for the establishment of a cranioplasty registry and am interested in the long term outcomes of patients following head injury and cranial reconstruction. 

I also conduct research in a wide range of neurosurgical conditions in collaboration with other researchers and students and am always looking for new areas to become involved in. 

Publications

Publications

Key publications

Edlmann E, Whitfield PC, Kolias A & Hutchinson PJ (2021) 'Pathogenesis of Chronic Subdural Hematoma: A Cohort Evidencing De Novo and Transformational Origins' Journal of Neurotrauma 38, (18) 2580-2589 , DOI Open access
Hutchinson PJ, Edlmann E, Bulters D, Zolnourian A, Holton P, Suttner N, Agyemang K, Thomson S, Anderson IA & Al-Tamimi YZ (2020) 'Trial of Dexamethasone for Chronic Subdural Hematoma' New England Journal of Medicine 383, (27) 2616-2627 , DOI Open access

Key publications are highlighted

Journals
Articles
Stubbs DJ, Davies BM, Dixon-Woods M, Bashford TH, Braude P, Bulters D, Camp S, Carr G, Coles JP & Dhesi J (2023) 'Protocol for the development of a multidisciplinary clinical practice guideline for the care of patients with chronic subdural haematoma' Wellcome Open Research 8, 390-390 Publisher Site , DOI
Edlmann E, Maripi H & Whitfield P (2023) 'Systematic review on traumatic intracranial haemorrhage in patients on anti-thrombotic medications; haemorrhage progression, thrombosis, and anti-thrombotic recommencement' Neurosurgical Review 46, (1) , DOI
Gillespie CS, Fung KW, Alam AM, Yanez Touzet A, Dhesi J, Edlmann E, Coles J, Menon DK, Hutchinson PJ & Stubbs DJ (2023) 'How does research activity align with research need in chronic subdural haematoma: a gap analysis of systematic reviews with end-user selected knowledge gaps' Acta Neurochirurgica , DOI
Gillespie CS, Khanna S, Vivian ME, McKoy S, Yanez Touzet A, Edlmann E, Stubbs DJ & Davies BM (2023) 'Is information provided within chronic subdural haematoma education resources adequate? A scoping review' PLOS ONE 18, (4) e0283958-e0283958 , DOI Open access
Edlmann E & Muquit S (2023) 'Machine learning driven prediction of cerebrospinal fluid rhinorrhoea following endonasal skull base surgery: A multicentre prospective observational study' Frontiers in Oncology 13, , DOI Open access
Edlmann E (2023) 'CSF rhinorrhoea after endonasal intervention to the skull base (CRANIAL): A multicentre prospective observational study' Frontiers in Oncology 12, , DOI Open access
Woodfield J, Hoeritzauer I, Jamjoom AAB, Jung J, Lammy S, Pronin S, Hannan CJ, Watts A, Hughes L & Moon RDC (2022) 'Presentation, management, and outcomes of cauda equina syndrome up to one year after surgery, using clinician and participant reporting: a multi-centre prospective cohort study' The Lancet Regional Health - Europe 24, 100545-100545 , DOI Open access
Chari A, Lee KS, Alamri A, Hutchinson PJA, Kolias AG & Edlmann E (2022) 'Could a Medication Help With Bleeding Between the Skull and the Brain?' Frontiers for Young Minds 10, , DOI Open access
Edlmann E, Giorgi-Coll S, Thelin EP, Hutchinson PJ & Carpenter KLH (2022) 'Dexamethasone reduces vascular endothelial growth factor in comparison to placebo in post-operative chronic subdural hematoma samples: A target for future drug therapy?' Frontiers in Neurology 13, , DOI Open access
Copley PC, Tadross D, Salloum N, Woodfield J, Edlmann E, Poon M, Khan S & Brennan PM (2022) 'A systematic review identifying outcome measures used in evaluating adults sustaining cervical spine fractures' European Spine Journal , DOI Open access
Woodfield J, Edlmann E, Black PL, Boyd J, Copley PC, Cranswick G, Eborall H, Keerie C, Khan S & Lawton J (2022) 'Duration of External Neck Stabilisation (DENS) following odontoid fracture in older or frail adults: protocol for a randomised controlled trial of collar versus no collar' BMJ Open 12, (7) , DOI Open access
Chari A, Piper RJ, Edlmann E, Woodfield J, Brennan PM, Turner C, Jenkinson MD, Hutchinson PJ, Kolias AG & Fountain DM (2022) 'Delivering Large-Scale Neurosurgical Studies in the UK: The Impact of Trainees' World Neurosurgery 161, 343-349 , DOI Open access
Stubbs DJ, Davies B, Hutchinson P, Menon DK, Bashford TH, Edlmann E, Bateman A, Braude P, Burnstein R & Camp S (2022) 'Challenges and opportunities in the care of chronic subdural haematoma: perspectives from a multi-disciplinary working group on the need for change' British Journal of Neurosurgery 1-9 , DOI Open access
Lee KS, Yordanov S, Stubbs D, Edlmann E, Joannides A & Davies B (2021) 'Integrated care pathways in neurosurgery: A systematic review' PLOS ONE 16, (8) , DOI Open access
Holl DC, Chari A, Iorio-Morin C, Dammers R, van der Gaag NA, Kolias AG, Hutchinson PJ & Edlmann E (2021) 'Study Protocol on Defining Core Outcomes and Data Elements in Chronic Subdural Haematoma' Neurosurgery 89, (4) 720-725 , DOI Open access
Edlmann E, Copley P, Hughes M & Woodfield J (2021) 'Letter to the Editor. A UK perspective on gender diversity in American neurosurgery training programs' Journal of Neurosurgery 1-2 , DOI Open access
Fountain DM, Henry J, Honeyman S, O’Connor P, Sekhon P, Piper RJ, Edlmann E, Martin M, Whiting G & Turner C (2021) 'First Report of a Multicenter Prospective Registry of Cranioplasty in the United Kingdom and Ireland' Neurosurgery 89, (3) 518-526 , DOI Open access
Edlmann E, Whitfield PC, Kolias A & Hutchinson PJ (2021) 'Pathogenesis of Chronic Subdural Hematoma: A Cohort Evidencing De Novo and Transformational Origins' Journal of Neurotrauma 38, (18) 2580-2589 , DOI Open access
Edlmann E & McMahon C (2021) 'Balancing risks and benefits when recommencing oral anticoagulants after major bleeding' Thrombosis and Haemostasis Publisher Site , DOI Open access
Woodfield J, Copley PC, Hughes M & Edlmann E (2021) 'The gender gap in European neurosurgical conference presentations' Neurosurgical Focus 50, (3) , DOI Open access
Hutchinson PJ, Edlmann E, Bulters D, Zolnourian A, Holton P, Suttner N, Agyemang K, Thomson S, Anderson IA & Al-Tamimi YZ (2020) 'Trial of Dexamethasone for Chronic Subdural Hematoma' New England Journal of Medicine 383, (27) 2616-2627 , DOI Open access
Edlmann E & Whitfield PC (2020) 'The changing face of neurosurgery for the older person' Journal of Neurology 267, (8) 2469-2474 Publisher Site , DOI Open access
Edlmann E, Holl DC, Lingsma HF, Bartek J, Bartley A, Duerinck J, Jensen TSR, Soleman J, Shanbhag NC & Devi BI (2020) 'Systematic review of current randomised control trials in chronic subdural haematoma and proposal for an international collaborative approach' Acta Neurochirurgica 162, (4) 763-776 , DOI Open access
Allison A, Edlmann E, Kolias AG, Davis-Wilkie C, Mee H, Thelin EP, Turner C, Hutchinson PJ & Bond S (2019) 'Statistical analysis plan for the Dex-CSDH trial: a randomised, double-blind, placebo-controlled trial of a 2-week course of dexamethasone for adult patients with a symptomatic chronic subdural haematoma' Trials 20, (1) , DOI Open access
Jung J, Tailor J, Dalton E, Glancz LJ, Roach J, Zakaria R, Lammy S, Chari A, Budohoski KP & Livermore LJ (2019) 'Management evaluation of metastasis in the brain (MEMBRAIN)—a United Kingdom and Ireland prospective, multicenter observational study' Neuro-Oncology Practice 7, (3) 344-355 , DOI Open access
Fountain DM, Davies SCL, Woodfield J, Kamel M, Majewska P, Edlmann E, Jamjoom AAB, Hoeritzauer I, Waqar M & Mahoney DE (2019) 'Evaluation of nationwide referral pathways, investigation and treatment of suspected cauda equina syndrome in the United Kingdom' British Journal of Neurosurgery 33, (6) 624-634 , DOI Open access
Edlmann E, Thelin EP, Caldwell K, Turner C, Whitfield P, Bulters D, Holton P, Suttner N, Owusu-Agyemang K & Al-Tamimi YZ (2019) 'Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase' Scientific Reports 9, (1) 0-0 , DOI Open access
Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D & Thomson S (2019) 'Correction to: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial' Trials 20, (1) , DOI Open access
Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D & Thomson S (2018) 'Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial' Trials 19, (1) 0-0 , DOI Open access
Blencowe N, Glasbey J, Heywood N, Kasivisvanathan V, Lee M, Nepogodiev D, Wilkin R, Allen S, Borakati A & Bosanquet D (2017) 'Recognising contributions to work in research collaboratives: Guidelines for standardising reporting of authorship in collaborative research' International Journal of Surgery 52, 355-360 , DOI
Chari A, Jamjoom AA, Edlmann E, Ahmed AI, Coulter IC, Ma R, May P, Brennan PM, Hutchinson PJA & Kolias AG (2017) 'The British Neurosurgical Trainee Research Collaborative: Five years on' Acta Neurochirurgica 160, (1) 23-28 , DOI Open access
Kolias A, Edlmann E & Hutchinson PJ (2017) 'The role of pharmacotherapy in the management of chronic subdural haematoma' Swiss Medical Weekly , DOI
Edlmann E, Giorgi-Coll S, Whitfield PC, Carpenter KLH & Hutchinson PJ (2017) 'Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy' Journal of Neuroinflammation 14, (1) , DOI Open access
Chari A, Hocking KC, Edlmann E, Turner C, Santarius T, Hutchinson PJ & Kolias AG (2016) 'Core Outcomes and Common Data Elements in Chronic Subdural Hematoma: A Systematic Review of the Literature Focusing on Baseline and Peri-Operative Care Data Elements' Journal of Neurotrauma 33, (17) 1569-1575 , DOI Open access
Chapters
Edlmann E & Muquit S (2021) 'Non-functioning Pituitary Adenoma' Rhinology and Anterior Skull Base Surgery Springer International Publishing 161-168 , DOI
Edlmann E & Whitfield PC (2020) 'Neurosurgical Complications of Head Injury' Traumatic Brain Injury Cambridge University Press 247-257 , DOI
Edlmann E, Hutchinson PJ & Kolias AG (2017) 'Chronic Subdural Haematoma in the Elderly' Brain and Spine Surgery in the Elderly Springer International Publishing 353-371 , DOI
Conference Papers
Edlmann E, Kolias A, Thelin E, Gatt D, Al-Tamimi Y, Owusu-Agyemang K, Suttner N, Holton P, Bulters D & Allison A (2019) 'TP1-3 Final phase of recruitment and statistics analysis plan for Dex-CSDH trial' BMJ e10.4-e11 , DOI
Kolias A, Edlmann E, Chari A, Marcus H, Myint P, Nandi D, Warburton E, Belli A, Turner C & Bulters D (2016) 'A RANDOMISED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL OF A TWO-WEEK COURSE OF DEXAMETHASONE FOR ADULT PATIENTS WITH A SYMPTOMATIC CHRONIC SUBDURAL HAEMATOMA (DEX-CSDH TRIAL)' A15-A16
Kolias A, Chari A, Edlmann E, Hocking K, Turner C, Santarius T & Hutchinson P (2016) 'CORE OUTCOMES AND COMMON DATA ELEMENTS IN CHRONIC SUBDURAL HAEMATOMA (CODE-CSDH)' A15-A15
Presentations and posters
Fountain D, Whiting G, Mee H, Edlmann E, Joannides A, Piper R, Turner CL, Kolias AG & Hutchinson PJ Fountain D, Whiting G, Mee H, Edlmann E, Joannides A, Piper R, Turner CL, Kolias AG & Hutchinson PJ 'The UK Cranioplasty Study and Development of the UK Cranial Reconstruction Registry' , DOI
Personal

Personal

Additional information

In addition to my passion for neurosurgery, I am a mother and a passionate advocate for the role of women in neurosurgery and academia. I have been invited to be part of an equality and diversity task force led by the EANS to help improve recruitment and working standards for diverse groups within neurosurgery. I think the establishment and availability of good role models in the field is essential and am always happy to be contact by students or colleagues with similar interests.