Original ResearchCulture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
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Conflicts of interest This author discloses the following: Daniel Zerbino is currently an employee of Mosaic Therapeutics. The remaining authors disclose no conflicts.
Funding Supported by grants from the Medical Research Council (New Investigator Research Grant), European Society of Paediatric Gastroenterology, Hepatology and Nutrition (networking grant), Guts UK Charity, British Society for Paediatric Gastroenterology, Hepatology and Nutrition, and by the National Institute for Health and Care Research Cambridge Biomedical Research Centre. Also supported by the University of California Los Angeles Broad Stem Cell Research Center Predoctoral Training Grant and the Rose Hills Foundation (S.L.); the University of California Los Angeles Broad Stem Cell Research Center Innovation Award and the Rose Hills Foundation, the CURE: Digestive Diseases Research Center at University of California Los Angeles Pilot and Feasibility Study Award (center grant P30 DK 41301), and the University of California Los Angeles Clinical and Translational Science Institute/Broad Stem Cell Research Center/David Geffen School of Medicine Regenerative Medicine Theme Award (D.L.J.); Crohn’s in Childhood Research Organization (J.K.); and by core funding from the European Molecular Biology Laboratory (D.R.Z. and R.D.E.).
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Authors share co-first authorship
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Authors share co-senior authorship.